If losing weight is to be justified then there should be convincing evidence that there will be definite benefits to health for those who actually succeed in reducing their body weight. In an investigation in which 2453 men and 2739 women aged 45 to 74 were monitored initially in the period 1971-1975 and followed up until 1987, it was found that there was a strong association between weight loss and the risk of death from cardiovascular disease among both men and women with BMI in the range 26-29….the overweight category. For men this risk had increased by a factor of 2 and for women it had increased by a factor of well over 3 compared with those who did not lose weight. Similar results were obtained if the analysis was restricted to non-smokers (1). In the Honolulu Heart Study, 6537 Japanese-American men aged 45 to 68 in 1965 and living in Hawaii, were monitored from 1973 to 1988 during which time there were 1217 deaths. The results are shown in Table 1. It is quite clear that there has been a notable increase in the death rate of those who lost weight. By contrast, those who gained up to 4.5kg had a reduced death rate while those who gained more than that did not experience any increase in mortality rate when compared with those whose weight did not vary(2)....Read More
At any given time there are large numbers of people who are attempting to lose weight. For example a survey conducted in Denmark found that 25% of people classified as underweight were slimming (1). The results for all BMI categories are in Table 1 TABLE 1. PROPORTION SLIMMING IN THE DIFFERENT BMI CATEGORIES BASED ON SURVEY CONDUCTED IN DENMARK BMI category % attempting to lose weight Underweight 25 Normal weight 38 Overweight 54 Obese 77 A survey of 16,486 university students in 21 European countries found that only 8% were overweight and that less than 1% was obese. Nevertheless many of them perceived themselves to be overweight. Consequently 44% of women and 175 of men were trying to lose weight. It was also observed that 14% of women and 35% of men were dieting (2). In the USA, 118,265 men and women located all over the country participated in a telephone survey T he results showed that 29% of men and 44% of women were trying to lose weight. This included 28.7% of women and 8.6% of men with a BMI that was normal. For those who were overweight as determined by BMI the values were 59.6% for women and 35.7% for men. In fact only 1/3 of the men trying to lose weight were classed as obese. For women only ¼ were obese (3). According to information...Read More
A major study has reported that women who use statins have a much higher risk of developing diabetes mellitus(DM) when compared women who do not. This is one the results obtained in the Women’s Health Initiative(WHI) which is being conducted in the USA(1). The WHI recruited 161,808 postmenopausal women aged 50 to 79 years at 40clinical centres across the USA between 1993 and 1998. This study is based on an analysis of data available up to 2005 from 153,840 participants. Of these 10,834 were statin users. The average age of all those involved was just over 63 years. Those who used statins had an incidence of DM which was 71% higher than those who did not. The increased risk of DM was observed for all types of statin. There was no difference between high- and low-potency statins. One particularly interesting feature of the results was the relatively high risk of developing DM in those who had a BMI of 25 or less. This BMI is considered to be the ideal but nevertheless statin users had more than double the risk of developing DM as compared with the non-users. TABLE 1 VARIATION IN RELATIVE RISK OF DEVELOPING DIABETES WITH BODY MASS INDEX(BMI) BMI STATIN USER RELATIVE RISK <25.0 YES 2.50 NO 1.00(Reference) 25.0-29.9 YES 1.91 NO 1.00(Reference) >30.0 YES 1.23 NO 1.00(Reference) It is absolutely crucial to recognise that...Read More
There is now ample evidence to show that low cholesterol (TC) per se is linked to a range of adverse side-effects including an increase in the incidence of violent deaths and suicide. A meta-analysis found that observational studies (including cohort, case–control, and cross-sectional studies) consistently showed increased violent death and violent behaviours in persons with low TC levels. Some meta-analyses of randomized trials found excess violent deaths in men without heart disease who were receiving cholesterol-lowering therapy. Experimental studies showed increased violent behaviours in monkeys assigned to low-cholesterol diets. Human and animal research indicates that low or lowered TC levels may reduce central serotonin activity, which in turn is causally linked to violent behaviour. Many trials support a significant relation between low or lowered TC levels and violence (1). In 1990, Muldoon conducted a review of 6 different trials to study the effect of cholesterol-lowering (2). These involved 24,847 men whose mean age was 47.5 years. The follow-up period consisted of 119,000 person-years and 1,147 deaths. It was confirmed that deaths from heart disease did decrease as the TC was lowered but deaths from other causes increased so that the all-cause mortality was not altered. Although there were 28 fewer deaths from CHD there were actually 29 more deaths from suicides and murder. The realities of the violent behaviour that can arise as a result of the use of...Read More
The justification for the prescription of statins is that they lower the level of cholesterol in the blood(TC). As a consequence it is argued there will be a reduction in the risk of developing heart disease. However as I have demonstrated in previous blogs (BLOGS 8 and 14)this argument does not stand up to rigorous examination. When investigations have been done which specifically consider the effect of statin therapy on the incidence of heart disease the results are by no means clear-cut. Essentially this is what has been discovered: In all women there is absolutely no reliable evidence to show that there is any improvement in life expectancy The same result has been obtained for men who have not suffered from heart disease For men who have had heart disease there is a marginal improvement but this is very small. It is necessary to treat 50 men for 5 years in order that one will benefit! On the other hand there are numerous reports of damaging side-effects which are related to the use of the statin medication. Here are 3 case studies from patients who visited hospitals in North Wales (1). A 63-year-old lady had pains in her right thigh and knee which she believed had been caused by a 3-mile walk while she was on holiday. A month after her initial visit she returned to the hospital...Read More
- 304. Sulphonylureas increase cardiac deaths but are still recommended for use after Metformin in type two diabetics in Scotland.
- 303. Statins: Why it is crucial to have a comprehensive picture
- 302. The Conventional Treatment of Type 2 Diabetes (T2D)
- 301. Many Faces of Insulin Resistance
- 300. HEALTHY EATING: THE BIG MISTAKE
- Personal examples which confirm that the official line on T2D to increase carbs is not only wrong but dangerous
about 44 mins ago
- The justification for the National Cholesterol Education Program in the USA is based on the manipulation of some re… https://t.co/kHVJvLl4sA
about 1 hour ago
- How Petr Skrabenek ridiculed the conventional dietary guidelines over 20 years ago.
about 1 hour ago
- PHE advises unbelievable intakes of carbs. Even higher than the dubious SACN recommendations.
about 2 hours ago
- Papers which had to be released by Merck because of the VIoxx scandal (up to 500,000 premature deaths) reveal how t… https://t.co/BxEYubp569
about 2 hours ago