There is now ample evidence to show that low cholesterol (TC) per se is linked to a range of adverse side-effects including an increase in the incidence of violent deaths and suicide. A meta-analysis found that observational studies (including cohort, case–control, and cross-sectional studies) consistently showed increased violent death and violent behaviours in persons with low TC levels. Some meta-analyses of randomized trials found excess violent deaths in men without heart disease who were receiving cholesterol-lowering therapy. Experimental studies showed increased violent behaviours in monkeys assigned to low-cholesterol diets. Human and animal research indicates that low or lowered TC levels may reduce central serotonin activity, which in turn is causally linked to violent behaviour. Many trials support a significant relation between low or lowered TC levels and violence (1). In 1990, Muldoon conducted a review of 6 different trials to study the effect of cholesterol-lowering (2). These involved 24,847 men whose mean age was 47.5 years. The follow-up period consisted of 119,000 person-years and 1,147 deaths. It was confirmed that deaths from heart disease did decrease as the TC was lowered but deaths from other causes increased so that the all-cause mortality was not altered. Although there were 28 fewer deaths from CHD there were actually 29 more deaths from suicides and murder. The realities of the violent behaviour that can arise as a result of the use of...Read More
The justification for the prescription of statins is that they lower the level of cholesterol in the blood(TC). As a consequence it is argued there will be a reduction in the risk of developing heart disease. However as I have demonstrated in previous blogs (BLOGS 8 and 14)this argument does not stand up to rigorous examination. When investigations have been done which specifically consider the effect of statin therapy on the incidence of heart disease the results are by no means clear-cut. Essentially this is what has been discovered: In all women there is absolutely no reliable evidence to show that there is any improvement in life expectancy The same result has been obtained for men who have not suffered from heart disease For men who have had heart disease there is a marginal improvement but this is very small. It is necessary to treat 50 men for 5 years in order that one will benefit! On the other hand there are numerous reports of damaging side-effects which are related to the use of the statin medication. Here are 3 case studies from patients who visited hospitals in North Wales (1). A 63-year-old lady had pains in her right thigh and knee which she believed had been caused by a 3-mile walk while she was on holiday. A month after her initial visit she returned to the hospital...Read More
The above is the title of a film made by Justin Smith which describes the way in which science is being manipulated and corrupted in order to underpin the sales of statins which generate billions of dollars for the pharmaceutical industry every year. For a short period this film can be viewed free of charge using the link below: http://www.youtube.com/watch?v=iZctVYxiW2w Although it lasts for just over an hour I strongly recommend that as many people as possible take the time to view. Here are just a few of the points which are dealt with in the film: The original work by Ancel Keyes which is the foundation of the Diet/Heart Theory is fundamentally flawed. Keys used data from 6 countries to show that there is a good relationship between the amount of fat in the diet, the cholesterol in the blood and the incidence of heart disease. If he had included data from 22 countries which were available then he would have found that such relationships simply did not exist. Information from the British Heart Foundation shows that in Great Britain for men aged 65-74 there has been a fall in the proportion with high cholesterol from 87% in 1994to 54% in 2006 yet the prevalence of heart disease has remained constant at 21%. In Great Britain, women in the lower socio-economic groups are 5 times more likely to...Read More
In BLOG 15, I explained that there are serious doubts about the rationale which underpins the recommendation to increase the intake of polyunsaturates (PUFAs) which are the omega-6 fatty acids(omega 6s). Nevertheless foods which are high in PUFAs continue to be promoted as healthy. As recently as 2009 the American Heart Association (AHA) reviewed its position. It was concluded that the combined results of a range of studies provided: “ evidence that replacing saturated fat or refined carbohydrates….with omega-6 PUFAs reduces CHD risk” It went on to recommend that consumption of at least 5% to 10% of energy from omega 6s would reduce the risk of heart disease relative to lower intakes. Furthermore higher levels appear to be safe and would probably be beneficial(1). However the quality of much of the research used to justify this recommendation has been seriously questioned. In a thorough examination of the relevant critical investigations, Chris Ramsden and colleagues discovered that in a number of these trials mixtures of omega-3s and omega-6s were actually used but it had been assumed that only omega 6s were present. When the investigations were separated into those which contained mixtures and those which consisted of omega-6s only a very different picture emerges. Those with mixed omega-3/omega-6s did actually result in a significant reduction in the risks of non-fatal heart attacks of 27%. For non-fatal heart attacks plus CHD...Read More
In my last post (BLOG 23) I showed there is convincing evidence that the fat present in milk is linked with specific health benefits. In recent years there has been growing interest in the CLAs which is the term used to describe the positional and geometric isomers of linoleic acid (LA). These have either one or both of the double bonds in the cis (c) or trans (t) conformation which are separated by a simple carbon-carbon linkage. CLA isomers are naturally found in dairy and meat products of ruminant origin such as cows, sheep and goats. About 30 years ago it was discovered that CLA was an effective inhibitor of the mutagens that were produced in hamburgers when they were grilled. Since then evidence has emerged which demonstrate that CLA can reduce the risks of developing heart disease, inflammation, diabetes, bone density loss and immune dysfunction. The two major CLA isomers are rumenic acid (c9, t11 (C18:2)) and the t10, c12 isomer. Typically the CLA in cow’s milk contains 85-90% rumenic acid. Experiments with small animals have shown that diets with a relatively high content of rumenic acid are associated with improving cardiovascular health, anti-carcinogenic properties and improved immune function. The evidence also shows that the HDL cholesterol is raised while the triglycerides are lowered(1). The relationship between the consumption of high-fat dairy products and the incidence...Read More
- Unbelievable! Latest "Dietary Guidelines for Americans" based on discredited science.
about 30 mins ago
- Meat and dairy industries should go on the offensive. Sat fats are good for you.Grassfed especially good news.
about 51 mins ago
- #Statins provide false reassurances that may discourage patients from taking the steps that actually reduce CVD.
about 1 hour ago
- Minnesota study shows lowering cholesterol increased all-cause mortality by 35% in those aged over 65 years old
about 2 hours ago
- Has anyone got "Insulin Resistance for Dummies" which should be required reading for this SACN committee?
about 2 hours ago