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Author: VWheelock

248. Big Pharm. The Great Big Drugs Rip-off (Part 1)

The major international drug companies have an appalling record with respect to compliance with the law. On many occasions they have been called to account and required to pay massive sums as a result. This record is convincing evidence that these companies cannot be trusted to operate ethically. This blog and the next two will summarise some examples of the actions by the regulatory authorities in the UK and the USA. In view of the huge expectations many people have about the drugs they are using, I believe this information should be widely disseminated. Action against Pfizer in the UK The Competition and Markets Authority (CMA) in the UK has imposed a record fine of £84.2 million on the pharmaceutical manufacturer Pfizer, and a £5.2 million fine on the distributor Flynn Pharma for charging excessive and unfair prices for phenytoin sodium capsules in breach of the competition law. This drug is used to treat epilepsy (1). The CMA has also ordered the companies to reduce their prices. The original price was that paid when the product was sold under the brand name Epanutin. The price of branded products are controlled by regulation. What happened was that in September 2012, Pfizer sold the UK distribution rights for Epanutin to Flynn Pharma, which de-branded (or ‘genericised’) the drug, meaning that it was no longer subject to price regulation. Since September 2012,...

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247. Jorge Luis Garcia Provides more Evidence in Support of Low Carb High Fat (LCHF) Diets

I am very grateful to Jorge for the information that I have used to prepare this blog. He is another individual who has had to discover this insight from his own efforts, which have only been possible because of the access to a wide range of resources available on the internet. It is a sad commentary on the mainstream professionals that so many are unaware of this knowledge or even worse actually dismiss it. Mother develops cancer Jorge is a specialist in dental prosthetics originally from Venezuela who moved to Florida in 2007. However in 2011 he returned home to look after his mother who was seriously and unable to cope on her own. She had suffered from hypertension for many years but her blood sugar was high and Jorge was convinced she was insulin resistant. She was on a long list of different medications, including statins. In July-August 2012, she noticed that the tonsil on her right side was swollen. Shortly after this she started coughing continually. As Jorge says:  “Everytime that I listen to her coughing I felt like somebody was punching me in the stomach.” Then in November of that year a biopsy showed that it was Stage III Cancer. The tumour grew very rapidly and his mother was eating almost nothing because it was so difficult to swallow. Jorge would prepare soups using a blender...

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246. Vitamin D: the evidence just gets stronger

There is no doubt that a low Vitamin D status is associated with a range of diseases and conditions of ill-health. If it can be confirmed that an inadequate intake of Vitamin D is a contributory factor then it follows that supplementation would have enormous benefits. However there is some debate on the level in the blood that has to be maintained in order to achieve optimum health. One of the big problems is that there have been few randomised controlled trials (RCTs), which can provide conclusive proof that supplementation is effective. Furthermore it is essential to ensure that the Vitamin D dose is sufficiently high to obtain a substantial increase in the blood concentration as estimated by the content of 25 (OH) Vitamin D. Vitamin D and cancer Much progress has been made on this topic by GrassrootsHealth. An investigation reported in 2007 produced very promising results on cancer incidence (1). 1180 women from rural areas in Nebraska were recruited and allocated to one of three different treatments, which consisted of: Controls who took a placebo (n=288); A supplement of calcium (n=445); A supplement of calcium plus Vitamin D (1,100 IU of Vitamin D3/day)(n=446). The study continued for 4 years, when the information was collated for the incidence of all cancers. Excluding those who developed cancer during the first year, to eliminate any that might have been initiated...

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245. Weight Loss for Treatment of Type 2 Diabetes (T2D)

Weight loss is an important aspect of the official policy for treating T2D. The recommendations are to increase the amount of fibre and to reduce fat, especially saturated fat. Specific advice includes: Increase consumption of foods such as wholegrain bread and cereals Choose foods that are low in fat – replace butter, ghee and coconut oil with low fat spreads and vegetable oil Choose skimmed and semi-skimmed milk, and low fat yoghurts If you have a BMI of 30kg/m2 or over you should lose weight by gradually by reducing your calorie intake and becoming more physically active. Losing 5-10% of your total body weight over the course of a year is considered to be a realistic initial target. Doubts about the guidance on weight loss There are two fundamental assumptions which underpin the recommendation to lose weight, namely: Excess weight is a direct cause of T2D (and other disease). Elimination of that excess will help to overcome T2D and improve health generally. It is an article of faith that the BMI should be in the normal range of 20-25kg/m2. Hence anyone with a higher value is advised to reduce their weight in order to achieve “normality”. However this has been questioned by various researchers. In particular Katherine Flegal and her team at the US Center for Disease Control (CDC) have found that with respect to life expectancy, the optimum BMI range...

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244. Is it any Wonder the Diabetes Prevention Programme in the UK is a Disaster?

It is quite obvious that the strategies for dealing with Type 2 Diabetes (T2D) in the UK (and in most other countries) are a complete failure. There is no indication that the disease is under control. In fact, all the projections expect the current rates of increase to be maintained for the foreseeable future. Latest initiative In March 2015, NHS England announced the Diabetes Prevention Programme (DPP) which is a joint initiative with Public Health England (PHE) and Diabetes UK (1).The object is to achieve a significant reduction in the number of people with T2D which is expected to be about 4 million if no action is taken. It is claimed that there have been well-designed trials conducted in Finland, the USA, Japan, China and India which show that reductions of up to 60% can be obtained in adults at high risk by means of intervention programmes to encourage changes in lifestyle. The justification has been developed by NICE. The initial proposals were subject to severe criticisms by specialists in the treatment of T2D (2). For example great emphasis was placed on the importance of weight loss and exercise in spite of limited evidence in support of this strategy. Furthermore this approach was not logical because many of the drugs recommended actually promote weight gain. As a consequence substantial amendments were made and a revised consultation document was issued....

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  • The dubious quality of the evidence used to justify #statins. https://t.co/LI14kYZpws
    about 35 mins ago
  • The football disaster in Sheffield shows how difficult it is to persuade politicians to tackle their mistakes. https://t.co/ckhCwtQO5S
    about 1 hour ago
  • How many more have to testify that the conventional approach to T2D does not work for the authorities to listen? https://t.co/icXIqSR2sr
    about 1 hour ago
  • Despite doubts about the benefits the case for Vitamin D supplementation remains very convincing. https://t.co/OFBrizQWgR
    about 2 hours ago
  • Low carb is the preferred way of losing weight by Italian gymnasts. https://t.co/q4rOY5Yxeu
    about 2 hours ago